Optimasi Formula Serum Wajah Menggunakan Ekstrak Etanol Daun Kelor (Moringa oleifera L.) sebagai Pelembap Kulit: Optimization of Face Serum Formula Using Ethanol Extract from Kelor Leaves (Moringa oleifera L.) as a Skin Moisturizer

Elinda Rahayu; Saraswati Ramadhani Priyono

doi:10.35760/jff.2025.v3i2.139

Penulis

Elinda Rahayu Universitas Gunadarma Penulis
Saraswati Ramadhani Priyono Universitas Gunadarma Penulis

DOI:

https://doi.org/10.35760/jff.2025.v3i2.139

Kata Kunci:

Antioxidant, Ethanol Extract of Moringa oleifera L. Leaves, Formulation, Facial Serum, Skin Moisturizing

Abstrak

Moringa (Moringa oleifera L.) is a member of the Moringaceae family that is rich in flavonoids and phenolics, especially in the leaves, with potential as an antioxidant and skin moisturizer. Serum is a preparation made with low viscosity so that it can deliver a thin film of active substances to the skin surface and has a high water content so that it can hydrate the skin. This study aims to optimize the formula of a face serum based on ethanol extract of moringa leaves. The extract was obtained using the maceration method and tested at concentrations of 2%, 4%, and 6%. The highest antioxidant activity was shown at a concentration of 6%, which was used as the optimal concentration in formulations with variations of 5%, 10%, and 15% glycerin. Antioxidant activity was tested in vitro using the DPPH method with UV-Vis spectrophotometry, while skin moisture was tested using a moisture skin analyzer. The results showed that all formulations met physical quality standards and had moderate to strong antioxidant activity with IC₅₀ values of F0 (36,772 ppm), F1 (26,966 ppm), F2 (25,300 ppm), and F3 (23,591 ppm). Increased concentrations of extract and glycerin were associated with decreased IC₅₀ values and increased moisturizing effects, with formula 4 producing the most optimal performance.

Unduhan

Data unduhan tidak tersedia.

Biografi Penulis

Elinda Rahayu, Universitas Gunadarma

Program Studi Farmasi, Fakultas Ilmu Kesehatan dan Farmasi
Saraswati Ramadhani Priyono, Universitas Gunadarma

Program Studi Farmasi, Fakultas Ilmu Kesehatan dan Farmasi

Referensi

[1] Dhea Dani BY, Wahidah BF, Syaifudin A. Etnobotani Tanaman Kelor (Moringa oleifera Lam.) di Desa Kedungbulus Gembong Pati. Al-Hayat: Journal of Biology and Applied Biology 2019; 2: 44.

[2] Susanty, Ridnugrah N.A., Chaerrudin A, et al. Aktivitas Antioksidan Ekstrak Daun Kelor (Moringa oleifera) Sebagai Zat Tambahan Pembuatan Moisturizer. Jurnal Nasional Sains dan Teknologi 2019; 1–7.

[3] Nurmala T, Handayani RP, Jamani F, et al. Kedelai (Glycine max L) Untuk Mengatasi Kulit Kering. 2019.

[4] Andrini N. Karakteristik Dan Perawatan Kulit Untuk Orang Asia. 4, https://jurnal.umsu.ac.id/index.php/JPH (2023).

[5] Butarbutar MET, Chaerunisaa AY. Peran Pelembab dalam Mengatasi Kondisi Kulit Kering. Majalah Farmasetika; 6. Epub ahead of print 21 October 2020. DOI: 10.24198/mfarmasetika.v6i1.28740.

[6] Liandhajani, Fitria N, Padua Ratu A. Karakteristik Dan Stabilitas Sediaan Serum Ekstrak Buah Kersen (Muntingia calabura L.) Dengan Variasi Konsentrasi. 2022.

[7] Rahmavika T, Murdiana HE, Rawar A. Formulasi dan Uji Antioksidan Serum Minyak Atsiri Kulit Jeruk Nipis (Citrus aurantifolia) Menggunakan Vitamain E Metode DPPH. 2023.

[8] Aisyah S, Hj Siti Sulanjari D. Pengaruh Penambahan Ekstrak Kulit Buah Manggis Terhadap Kualitas Sabun Transparan. 2020.

[9] Leonita Manurung B, Monica E, Ma Chung U, et al. Formulasi Dan Evaluasi Antioksidan Daun Kelor Moringa oleifera L. Dalam Sediaan Serum Dengan Metode Senyawa Radikal DPPH. 2023.

[10] Dachi K, Sudewi, Zebua NF, et al. Uji Efektivitas Antioksidan Menggunakan Spektrofotometri Uv-Visible Pada Formulasi Ekstrak Etanol Daging Buah Kelubi (Eleiodoxa conferta (Griff.) Burret) Sediaan Krim Pelembab, https://ejurnal.ung.ac.id/index.php/jjhsr/index (2023).

[11] Leny L, Rudang SN, Ginting I, et al. Formulasi Sediaan Lulur Krim Dari Ekstrak Etanol Daun Pepaya (Carica papaya L.) Sebagai Pelembab Kulit. Journal of Islamic Pharmacy 2023; 8: 22–26.

[12] Depkes RI. Farmakope Herbal Indonesia Edisi II. Jakarta, 2017.

[13] Mursyid AM, Zulkarnain I, Khusnia. Formulasi Serum Ekstrak Daun Kemangi (Ocimum basilicum. L) Sebagai Antioksidan. Makassar Pharmaceutical Science Journal 2023; 1: 2023–2066.

[14] Faradila SN, Prabandari R, Kusuma IY. Pengaruh Variasi Konsentrasi Gliserin Sebagai Humektan Terhadap Stabilitas Sediaan Pasta Gigi Ekstrak Etanol Daun Salam (Syzygium polyanthum (wight) Walp). Pharmacy Genius Journal 2022; 1: 27.

[15] Wulandari GA, Veronika P, Yamlean Y, et al. Pengaruh Gliserin Terhadap Stabilitas Fisik Gel Ekstrak Etanol Sari Buah Tomat (Solanum lycopersicum L.). 4.

[16] Rizkiah S, Okzelia SD, Efendi AS, et al. Formulasi Dan Evaluasi Gel Dari Ekstrak Kulit Putih Semangka (Citrullus Lanatus [Thunb.] Matsum. & Nakai) Sebagai Pelembap Kulit. Jurnal Sabdariffarma Tahun 2021; 9: 33–46.